Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
CACNA1C | Q13936 | calcium voltage-gated channel subunit alpha1 C | Ion channel | 1.00 | 0.510 | 0.846 |
ADCYAP1 | P18509 | adenylate cyclase activating polypeptide 1 | Signaling | 0.52 | 0.510 | 0.846 |
RAI1 | Q7Z5J4 | retinoic acid induced 1 | Transcription factor | 1.00 | 0.545 | 0.731 |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
NGLY1 | Q96IV0 | N-glycanase 1 | Enzyme | 1.5E-13 | 0.601 | 0.654 |
PAK3 | O75914 | p21 (RAC1) activated kinase 3 | Kinase | 0.99 | 0.569 | 0.731 |
TMEM106B | Q9NUM4 | transmembrane protein 106B | 0.33 | 0.590 | 0.462 | |
KDM5C | P41229 | lysine demethylase 5C | 1.00 | 0.581 | 0.538 | |
SLC19A3 | Q9BZV2 | solute carrier family 19 member 3 | Transporter | 0.10 | 0.610 | 0.692 |
SLC25A13 | Q9UJS0 | solute carrier family 25 member 13 | Transporter | 1.3E-24 | 0.617 | 0.500 |
GLDC | P23378 | glycine decarboxylase | Enzyme | 6.6E-28 | 0.628 | 0.577 |
TSEN54 | Q7Z6J9 | tRNA splicing endonuclease subunit 54 | 1.8E-07 | 0.659 | 0.500 | |
HSD17B10 | Q99714 | hydroxysteroid 17-beta dehydrogenase 10 | Enzyme | 0.94 | 0.656 | 0.538 |
AMT | P48728 | aminomethyltransferase | 2.7E-03 | 0.674 | 0.692 | |
CLN8 | Q9UBY8 | CLN8 transmembrane ER and ERGIC protein | 3.6E-03 | 0.682 | 0.423 | |
GCSH | P23434 | glycine cleavage system protein H | 1.6E-03 | 0.760 | 0.385 |